TOCOMIN RESTORES ENDOTHELIUM-DEPENDENT RELAXATION IN THE DIABETIC RAT AORTA BY INCREASING NO BIOAVAILABILITY AND IMPROVING THE EXPRESSION OF ENOS

Tocomin Restores Endothelium-Dependent Relaxation in the Diabetic Rat Aorta by Increasing NO Bioavailability and Improving the Expression of eNOS

We aimed to determine whether tocomin, an extract from Cutlery palm oil that has a high tocotrienol content, was able to prevent diabetes-induced endothelial dysfunction.To induce type 1 diabetes streptozotocin (50 mg/kg) was injected into the tail vein of Wistar rats.Six weeks later the diabetic rats, and normal rats injected with citrate buffer,

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A randomized, open-label, single-visit crossover study simulating triple-drug delivery with Ellipta compared with dual inhaler combinations in patients with COPD

Job van der Palen,1,2 Wendy Moeskops-van Beurden,1 Carolyn M Dawson,3 Wai-Yee MELATONIN 3MG James,3 Andrew Preece,4 Dawn Midwinter,4 Neil Barnes,5 Raj Sharma6 1Department of Pulmonology, Medisch Spectrum Twente, Enschede, the Netherlands; 2Department of Research Methodology, Measurement, and Data Analysis, University of Twente, Enschede, the Nether

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Protein Signatures for Distinguishing Colorectal Cancer Liver Metastases from Primary Liver Cancer Using Tissue Slide Proteomics

Background: Colorectal cancer liver metastasis (CRLM) and hepatocellular carcinoma (HCC) are both high incidence tumors in China.In certain poorly differentiated cases they can exhibit comparable imaging and pathological characteristics, which impedes accurate clinical diagnosis.The use of protein-based techniques with tissue slides offers a more p

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